BioNucleiResultsEvidence-first

Verified result samples from the BioNuclei scientific substrate.

This page is intentionally about BioNuclei only. BioMCP, BioFM, BioWF and BioSkills have separate product pages and are not part of these benchmark results.

Independent validation

E7 · BBBC038

Independent evaluation completed on 670 images. Values below are retained scientific results, not illustrative numbers.

MetricVerified value
Dice0.753291
IoU0.688403
AJI0.550038
Boundary-F10.468323
Evidence context: independent BBBC038 validation, 670-image evaluation, with checkpoint/dataset/provenance verification retained by the release workflow.

Want to run BioNuclei yourself?

Use the practical workflow to inspect a fluorescence image, predict nuclear instances, evaluate against ground truth and inspect the resulting files and provenance.

Few-shot adaptation

E6 · Example retained fraction output

The 25% recovery artifact below is shown as a concrete evidence sample. It is not substituted for the final four-fraction aggregate.

25% fraction
0.110908

Dice

20/20 epochs · seed 42 · 8 adaptation images · standardized E6 execution path
25% fraction
0.059246

IoU

Same retained evidence artifact and provenance chain
25% fraction
0.055426

AJI

Machine-readable test output
25% fraction
0.151082

Boundary-F1

Machine-readable test output
Acceptance rule: E6 scientific closure requires all four standardized fractions (1%, 5%, 10%, 25%) plus aggregate/provenance verification. This page does not declare a result beyond what the retained evidence supports.
Result bundle example

What a user receives from a local BioNuclei run

The local package produces structured files that can be inspected independently of any language model.

{
  "n_instances": 42,
  "image_shape": [1024, 1024],
  "provenance": "provenance.json",
  "artifacts": [
    "segmentation_mask.tif",
    "overlay.tif",
    "measurements.csv",
    "results.json",
    "provenance.json"
  ]
}
Sample schema only: the instance count and image shape in this block illustrate the output structure and are not a benchmark result. Benchmark values are shown only in the verified tables above.